Niacinamide is a form of vitamin B3 that has become very popular in recent years. It is often touted as a skin treatment because of its ability to reduce redness and inflammation. What exactly does niacinamide do?

Niacinamide was discovered in 1937 by scientists at Parke Davis & Co., who were looking for ways to treat acne. They found that nicotinic acid (the precursor to niacinamide) had anti-inflammatory properties, and they began marketing it as a topical treatment for acne. Since then, it has gained popularity as a general skincare ingredient.

Niacinamide is a water-soluble derivative of Vitamin B3. It is commonly used as a moisturizer and anti-wrinkle agent. It also helps improve skin tone and texture.

Niacin’s are the active ingredients in Vitamin B3. The most common forms are Nicotinamide and Nicotinic Acid. Both are water-soluble derivatives of Vitamin B3.

Niacin is an organic compound with the chemical formula C5H6O2N2. It is a white crystalline solid. Its molecular weight is 148.13 g/mol. It can be synthesized from nicotinic acid or nicotinamide.

Niazanol is a synthetic form of niacinamide that is manufactured by BASF and sold under the trade name “Niacor”. It is a clear liquid with a pH of 7.0. It is used as a preservative in cosmetic products such as creams and lotions.

Benefits of Niacinamide

Niacinamide is an effective moisturizer and anti-inflammatory agent. It helps prevent moisture loss from the skin and reduces inflammation.

Niacinamide improves skin barrier function, and it prevents premature signs of skin aging. It boosts collagen production to smooth wrinkles and reduces discoloration.

Dermatologists recommend using nicotinamide cream to reduce acne. However, there isn’t enough evidence to say whether this treatment works better than other acne treatments.

Niacinamide Dosing

Niacinamide products should contain no more than 5% niacinamide. Some products may contain up to 10%. Always check the label before buying.

How to use Niacinamide

Apply 1% – 2% of a non-comedogenic moisturizing cream containing niacinamide twice daily. You may apply it directly on your face, neck, chest, arms, legs, hands, feet, scalp, or any area where you want to improve your skin condition.

You should avoid applying it near your eyes, mouth, nose, and genitals.

Do not apply more than two times per day.

If you have sensitive skin, test out a small amount first before applying full strength.

If you notice irritation after application, stop using the product immediately. Contact your doctor if symptoms persist.

What are niacinamide uses

It’s important to note that niacinamide is only one part of the skincare regimen. It’s also important to remember that it won’t replace all your other skincare products. The following conditions may require additional testing:

Acne:

Studies show that niacinamide may help reduce acne breakouts. However, there aren’t enough studies to determine whether it’s more effective than other acne treatments. If you’re interested in trying it, talk to your dermatologist about how much you need to take.

Skin Aging:

Studies suggest that niacinamide could help slow down the visible signs of aging. This includes improving fine lines and wrinkles.

Hyperpigmentation:

Some research suggests that niacinamide might be helpful for treating hyperpigmentation (dark spots). Talk to your dermatologist about using it.

Psoriasis:

There is limited evidence that niacinamide can help treat psoriasis. More research is needed to see if it will work.

Warts:

There is some evidence that niacinamides help to destroy warts. However, it hasn’t been studied extensively. Talk to your dermatologist to find out if it’s safe for you.

Rosacea:

There is some evidence that reason may help control rosacea. Talk to your dermatologist to find out if it will work for you.

Eczema:

There is some preliminary evidence that niacinamide may help

Skin cancer:

There is some preliminary evidence that nicotinamide may help prevent skin cancers.

Pigmentation disorders:

There is some limited evidence that niacin may help with pigmentation disorders. Talk to your dermatology about using it.

Wrinkles:

There is some early evidence that niacin may help with wrinkle reduction.

Eye problems:

There is some anecdotal evidence that niacinamide may help with dry eye syndrome. Talk to your ophthalmologist about using it

Sun damage

Use caution when using niacinamide during pregnancy and breastfeeding. There isn’t enough information available to know if it’s safe for these groups.

Side effects

The side effects of niacinamide vary based on what form it comes in. For example, topical creams may cause redness, itching, burning, peeling, flaking, or scaling. Topical gels may cause similar reactions. Oral supplements may cause stomach upset.

Is niacinamide safe to use during pregnancy?

Yes. Niacinamide is considered safe when taken orally and topically. There is some concern about using niacinamide while pregnant due to potential adverse reactions. If you’re pregnant, talk with your healthcare provider about possible risks.

Is there any risk of side effects?

While most people don’t experience side effects from niacinamide, some people do. These include redness, itching, burning, peeling, stinging, tingling, swelling, and blisters.

Topical niacinamide should be used cautiously in people with known allergies. Niacinamide can cause you to release histamines, which can lead to a rash or other skin problems. A patch test is recommended before using topical niacinamide.

Redness, itching, or swollen areas may occur after using this product. Wash the affected area and discontinue use if you notice these symptoms. This product should be used safely on other parts of your body.

Can niacinamide be combined with other skincare ingredients for maximum effect?

Niacinamide may be useful for treating acne. It works well alongside other active ingredients such as copper, folic acid, and zinc. Supplementing with hyaluronic acid increases absorption.

Conclusion

If you have sensitive skin, you might want to try niacinamide first. You can also experiment with different forms of niacinamide — such as topical creams, oral supplements, and topical gels — to determine which one works best for you.